Epilepsy and folate deficiency.

نویسندگان

  • R D Eastham
  • J Jancar
چکیده

Virus-free Blood L. R. I. Baker, M.D., and others ..... ....... 360 Relative Hazards in Smoking Sir Selywn Selwyn-Clarke, F.R.C.P......... 360 Toxic Effects of Intermittent Rifampicin G. W. Poole, M.R.C.P., and others ..... ..... 361 Streptokinase and Myocardial Infarction R. Heikinheimo, M.D ..................... 361 Epilepsy and Folate Deficiency R. D. Eastham, M.D., F.R.C.PATH., and J. Jancar, D.P.M ........................... 361 Diagnosis of Cystic Fibrosis A. G. F. Davidson, M.D., and Charlotte M. Anderson, F.R.A.C.P. .................... 362 Predicting Fetal Maturity Rosemary A. Underhill, M.B., and others .... 362 Solar Flares and the Concorde F. J. Ensell, G.M., F.R.C.S ................. 362 Uses of Allopurinol G. D. Kersley, F.R.C.P ................... 363 The New F.F.R. R. E. Steiner, F.R.C.P., F.F.R ............... 363 Misuse of Drugs Act 1971 S. Bradshaw, M.B ....................... 363 Responsibility of the Scientist C. de F. W. Goonaratna, M.B ............. 363 Anorexia Nervosa J. G. Scadding, F.R.C.P ................... 364 Ampicillin and Mononucleosis S. A. Haider, M.R.C.P ..................... 364 Confidential Information and Cervical Cytology D. Mary Pack, M.B ....................... 364 Trimethoprim and Sulphamethoxazole D. W. Dawson, F.R.C.P.ED., and R. C. Routledge, M.B.; Z. Farid, M.D. ..... ..... 364 Transporting Patients with Chest Injuries A. E. Young, M.B ....................... 364 Anticoagulant Interactions T. K. Clarke, M.B., D.A ................... 364 Vacuum Termination of Pregnancy Stella C. Lewis, M.R.C.O.G ................. 365 Infection from Arteriovenous Shunts M. Yudis, M.D. ........................ 365 Removal of Abnormal Protein C. B. Freeman, M.R.C.P ................... 365 Antileprosy Drugs W. H. Jopling, F.R.C.P.ED ................. 366 Hyposensitization Treatment W. J. H. Leckie, F.R.C.P.ED ............... 366 Future of Hospital Management R. W. Parnell, F.R.C.P. .................. 366 Motor Race Rescue Unit R. S. J. Martin ........................ 366 S. Luke's Medical Fellowship J. B. Gurney Smith, L.M.S.S.A., and Barbara J. Shuttleworth, B.M ..................... 366 Dissect J. R. Nolan, M.B .......................... 366 Normal Range for Serum Transaminases D. M. Goldberg, PH.D., M.R.C.PATH., and G. Ellis, B.SC. ............................ 366

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منابع مشابه

Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease.

The importance of intracellular folate metabolism is illustrated by the severity of symptoms and complications caused by inborn disorders of folate metabolism or by folate deficiency. We examined three children of healthy, distantly related parents presenting with megaloblastic anemia and cerebral folate deficiency causing neurologic disease with atypical childhood absence epilepsy. Genome-wide...

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Bilateral occipital calcification associated with celiac disease, folate deficiency, and epilepsy.

In a patient with celiac disease, folate and iron deficiency, and epilepsy, CT over a 4-month period showed parietoocipital calcifications in the corticomedullary junctions. The calcification was progressive, but it and the seizures stabilized after institution of a gluten-free diet and iron and folic acid supplements.

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Diagnosis and management of cerebral folate deficiency. A form of folinic acid-responsive seizures.

Folinic acid-responsive seizures (FARS) are a rare treatable cause of neonatal epilepsy. They have characteristic peaks on CSF monoamine metabolite analysis, and have mutations in the ALDH7A1 gene, characteristically found in pyridoxine-dependent epilepsy. There are case reports of patients presenting with seizures at a later age, and with folate deficiency due to different mechanisms with vari...

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Serum folate concentrations during pregnancy in women with epilepsy.

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Nutritional anemias in pregnant women

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Late diagnosis of cerebral folate deficiency: Fewer seizures with folinic acid in adult siblings

Cerebral folate deficiency is a genetically heterogeneous condition.(1) Mutations in FOLR1 are responsible for a rare but treatable form of cerebral folate deficiency (OMIM #613068).(1) The gene codes for folate receptor alpha (FRα), a specific CNS folate transporter. Individuals with FOLR1-related folate deficiency present with ataxia, dyskinesia, spasticity, seizures, and regression in cognit...

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عنوان ژورنال:
  • British medical journal

دوره 4 5783  شماره 

صفحات  -

تاریخ انتشار 1971